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Product Name Anti-MFSD7/AP Chinese Name 碱性磷酸酶(AP)标记的MFSD7蛋白抗体 Alias Major facilitator superfamily domain-containing protein 7; mfsd7; MFSD7_HUMAN; MYL5; Myosin light polypeptide 5 regulatory protein. Research Area Cell biology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, ) Applications WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 58kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human MFSD7 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
MFSD7 is a 560 amino acid multi-pass membrane protein that belongs to the major facilitator superfamily. Existing as three alternatively spliced isoforms, MFSD7 is likely a carrier that transports small solutes by using chemiosmotic ion gradients. Significantly, a related protein, MFSD2, may play a role in placenta morphogenesis and may also be involved in adaptive thermogenesis. The gene encoding MFSD7 maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.
Subcellular Location:
Membrane.
Similarity:
Belongs to the major facilitator superfamily.
Database links:Entrez Gene: 84179 Human
SwissProt: Q6UXD7 Human
Unigene: 567612 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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