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Product Name Anti-IER3IP1/AP Chinese Name 碱性磷酸酶(AP)标记的即早反应蛋白3相互作用蛋白1抗体 Alias HSPC039; IER3IP1; Immediate early response 3-interacting protein 1; IR3IP_HUMAN; PRO2309. Research Area Cell biology Signal transduction Cyclin Transporter Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) Applications WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 9kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human IER3IP1 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
IER3IP1 has a G-patch domain which is thought to function in the binding of RNA. The G-patch domain is associated with various proteins which exhibit functions which may include tumor suppression and DNA damage repair, suggesting that IER3IP1 may be involved in cellular responses to DNA damage. Matrine is a molecule that induces erythroid cell differentiation of K562 cells and the presence of the IER3IP1 gene is thought to increase matrine function, implying a possible role for IER3IP1 in erythroid cell differentiation.
Function:
May be involved in protein transport between endoplasmic reticulum and Golgi apparatus.
Subcellular Location:
Endoplasmic reticulum membrane.
Tissue Specificity:
Highest levels in heart, skeletal muscle, and kidney.
Similarity:
Belongs to the YOS1 family.
Database links:Entrez Gene: 66191 Mouse
SwissProt: Q9CR20 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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