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Product Name Anti-SCARA3/AP Chinese Name 碱性磷酸酶(AP)标记的细胞应激反应蛋白抗体 Alias APC7; Cellular stress response; Cellular stress response gene protein; CSR; CSR1; Macrophage scavenger receptor-like 1; MSLR1; MSRL1; SCAR3_HUMAN; SCARA3; Scavenger receptor class A member 3. Research Area Cell biology immunology The new supersedes the old Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, ) Applications WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 65kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SCARA3 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
This gene encodes a macrophage scavenger receptor-like protein. This protein has been shown to deplete reactive oxygen species, and thus play an important role in protecting cells from oxidative stress. The expression of this gene is induced by oxidative stress. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Function:
Seems to protects cells by scavenging oxidative molecules or harmful products of oxidation.
Subcellular Location:
Endoplasmic reticulum membrane. Golgi apparatus membrane. Endoplasmic reticulum and/or Golgi.
Tissue Specificity:
Expressed ubiquitously.
Similarity:
Contains 2 collagen-like domains.
Database links:Entrez Gene: 51435 Human
Entrez Gene: 219151 Mouse
Omim: 602728 Human
SwissProt: Q6AZY7 Human
SwissProt: Q8C850 Mouse
Unigene: 128856 Human
Unigene: 344095 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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