Product Name	Anti-Kv3.2/AP
Chinese Name	碱性磷酸酶（AP）标记的电压门控钾通道Kv3.2抗体
Alias	KCNC2; KSHIIIA; Kv 3.2; Kv3.2d voltage gated potassium channel; Potassium channel Kv3.2; Shaw related voltage gated potassium channel protein 2. KCNC2_HUMAN
Research Area	Cell biology  Neurobiology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Rabbit, Sheep, )
Applications	WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	70kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Kv3.2
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: Potassium channels contribute to maintaining cell volume, membrane potential, neuronal excitability and the secretion of transmitters, salt and hormones. Two families of potassium channels have been identified. One family includes the inwardly rectifying potassium channels whereas, the other family includes: voltage sensing (KV); big conductance, calcium activated (BKca); and small conductance, calcium activated (SK) potassium channels. Kv3.2 functions as a delayed rectifier type K+ channel activated by large membrane depolarizations. Function: Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. Channel properties are modulated by subunit assembly (By similarity) Subunit: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming subunits that can associate with modulating accessory subunits Subcellular Location: Membrane; Multi-pass membrane protein. Similarity: Belongs to the potassium channel family. Database links: Entrez Gene: 3747 Human Entrez Gene: 246153 Rat Omim: 176256 Human SwissProt: Q86W09 Human SwissProt: Q96PR1 Human SwissProt: P22462 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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