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Product Name Anti-HIATL1/AP Chinese Name 碱性磷酸酶(AP)标记的HIATL1蛋白抗体 Alias HIAL1_HUMAN; Hiatl1; Hippocampus abundant transcript-like protein 1. Research Area Cell biology Developmental biology Neurobiology Signal transduction Transporter Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, Dog, Pig, Horse, Rabbit, ) Applications WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 55kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human HIATL1 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
HIAT1 is a multi-pass membrane protein that may function as a sugar transporter and is expressed in adult and embryonic brain. The HIAT1 gene was first observed while analyzing for active genes in neonatal mouse hipposcampus. HIATL1 (Hippocampus abundant transcript-like protein 1) is a 506 amino acid multi-pass membrane protein that also belongs to the Major facilitator superfamily. The gene encoding HIATL1 maps to human chromosome 9, which consists of about 145 million bases and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.
Subcellular Location:
Membrane.
Similarity:
Belongs to the major facilitator superfamily.
Database links:Entrez Gene: 84641 Human
SwissProt: Q5SR56 Human
Unigene: 555996 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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