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Product Name Anti-FBF-1/AP Chinese Name 碱性磷酸酶(AP)标记的FBF-1蛋白抗体 Alias ALB; Fas (TNFRSF6) binding factor 1; Fas binding protein 1; fas-binding factor 1; FBF 1; FBF1; FBF1_HUMAN; FLJ00103; KIAA1863; Protein albatross. Research Area Cell biology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Horse, Sheep, ) Applications IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 125kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human FBF-1 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Keratin-binding protein required for epithelial cell polarization. Involved in apical junction complex (AJC) assembly via its interaction with PARD3. Required for ciliogenesis.
Function:
Keratin-binding protein required for epithelial cell polarization. Involved in apical junction complex (AJC) assembly via its interaction with PARD3. Required for ciliogenesis.
Subunit:
May interact with FAS cytoplasmic domain (By similarity). Interacts with PARD3.
Subcellular Location:
Cytoplasm; cytoskeleton; centrosome; centriole. Cytoplasm; cytoskeleton; spindle pole. Cell junction. Note: Associates with the mother centriole. Localizes to the apical junction complex (AJC) in epithelial cells.
Tissue Specificity:
Present in various epithelial cells (at protein level).
Database links:Entrez Gene: 85302 Human
SwissProt: Q8TES7 Human
Unigene: 720068 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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