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Rabbit Anti-EPB41L1/AP Conjugated antibody
Rabbit Anti-EPB41L1/AP Conjugated antibody
4.1N; Band 4.1 like protein 1; Band 4.1-like protein 1; DKFZp686H17242; E41L1_HUMAN; EPB41L 1; Epb41l1; Erythrocyte membrane protein band 4.1 like 1; KIAA0338; MGC11072; MRD11; Neuron type nonerythroid protein 4.1; Neuronal protein 4.1; Nonerythroid prote
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  • NO.:SL14606R-AP
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Pig,Cow,Horse,Rabbit,Sheep,Rhesus monkey)
    Applications:WB IHC-P IHC-F ICC
    concentration:1mg/ml
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Product Name Anti-EPB41L1/AP
Chinese Name 碱性磷酸酶(AP)标记的EPB41L1蛋白抗体
Alias 4.1N; Band 4.1 like protein 1; Band 4.1-like protein 1; DKFZp686H17242; E41L1_HUMAN; EPB41L 1; Epb41l1; Erythrocyte membrane protein band 4.1 like 1; KIAA0338; MGC11072; MRD11; Neuron type nonerythroid protein 4.1; Neuronal protein 4.1; Nonerythroid protein 4.1; Nonerythroid protein 4.1, neuron type; OTTHUMP00000030825; OTTHUMP00000030826; OTTHUMP00000030827; OTTHUMP00000030829.  
Research Area Cell biology  Signal transduction  Binding protein  Cell type markers  Cytoskeleton  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, Rhesus monkey)
Applications WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 88kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human EPB41L1
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
Erythrocyte membrane protein band 4.1 (EPB41) is a multifunctional protein that mediates interactions between the erythrocyte cytoskeleton and the overlying plasma membrane. The protein encoded by this gene is a neuronally-enriched protein that is structurally similar to EPB41. The encoded protein binds and stabilizes D2 and D3 dopamine receptors at the neuronal plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

Function:
May function to confer stability and plasticity to neuronal membrane via multiple interactions, including the spectrin-actin-based cytoskeleton, integral membrane channels and membrane-associated guanylate kinases.

Subcellular Location:
Cytoplasm; cytoskeleton.

Tissue Specificity:
Highest expression in brain, lower in heart, kidney, pancreas, placenta, lung and skeletal muscle.

Similarity:
Contains 1 FERM domain.

Database links:

Entrez Gene: 2036 Human

Entrez Gene: 13821 Mouse

Entrez Gene: 59317 Rat

Omim: 602879 Human

SwissProt: Q9H4G0 Human

SwissProt: Q9Z2H5 Mouse

SwissProt: Q9WTP0 Rat

Unigene: 722186 Human

Unigene: 20852 Mouse

Unigene: 20361 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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