TEL: +86 571 56623320 EMAIL: [email protected]
Product Name Anti-SHFM1/DSS1/AP Chinese Name 碱性磷酸酶(AP)标记的先天性裂手/裂足畸形相关蛋白DSS1抗体 Alias 26S proteasome complex subunit DSS1; Deleted in split hand/split foot 1; Deleted in Split-Hand/Split-Foot 1 region; ECD; SEM1; SHFD1; DSS1_HUMAN; SHFM1; SHSF1; Split hand/foot deleted protein 1; Split hand/foot malformation (ectrodactyly) type 1; Split hand/foot malformation type 1 protein. Research Area Cell biology Developmental biology Cyclin Ubiquitin Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Pig, Cow, Rabbit, ) Applications IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 8.3kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human DSS1 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
The product of this gene has been localized within the split hand/split foot malformation locus SHFM1 at chromosome 7. It has been proposed to be a candidate gene for the autosomal dominant form of the heterogeneous limb developmental disorder split hand/split foot malformation type 1. In addition, it has been shown to directly interact with BRCA2. It also may play a role in the completion of the cell cycle. [provided by RefSeq, Jul 2008]
Function:
The gene for DSS1 has been localized within the split hand/split foot malformation locus SHFM1 at chromosome 7. DSS1 has been proposed to be a candidate for the autosomal dominant form of the heterogeneous limb developmental disorder split hand/split foot malformation type 1. In addition, it has been shown to directly interact with BRCA2. It also may play a role in the completion of the cell cycle.
Subunit:
Part of the 26S proteasome. Interacts with the C-terminal of BRCA2.
Tissue Specificity:
Expressed in limb bud, craniofacial primordial and skin.
Similarity:
Belongs to the DSS1/SEM1 family.
Database links:Entrez Gene: 7979 Human
Omim: 601285 Human
SwissProt: P60896 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Scan Wechat Qrcode