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Product Name Anti-C9orf116/AP Chinese Name 碱性磷酸酶(AP)标记的9号染色体开放阅读框116抗体 Alias C9orf116; CI116_HUMAN; Pierce 1; UPF0691 protein C9orf116. Research Area Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Sheep, ) Applications WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 15kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human C9orf116 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
C9orf116 is a 136 amino acid protein that belongs to the UPF0691 family. Pierce 1 exists as two alternatively spliced isoforms, which are conserved in chimpanzee, dog, cow, mouse and rat. Pierce 1 is predominantly expressed in micrometastases and macrometastases of human small cell lung cancer. Pierce 1 is encoded by a gene that maps to chromosome 9, which consists of about 145 million bases, makes up 4% of the human genome and encodes nearly 900 genes. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with chromosome 9.
Similarity:
Belongs to the UPF0691 family.
Database links:Entrez Gene: 138162 Human
Omim: 614502 Human
SwissProt: Q5BN46 Human
Unigene: 414028 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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