Product Name	Anti-GANC/AP
Chinese Name	碱性磷酸酶（AP）标记的α-葡萄糖苷酶C抗体
Alias	Neutral alphaglucosidase C; Ganc; GANC_HUMAN; Glucosidase alpha neutral C; MGC138256; Neutral alpha glucosidase C; Neutral alpha-glucosidase C; Neutral alphaglucosidase C.
Research Area	Tumour  Cell biology  Signal transduction  Diabetes  The new supersedes the old
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Horse, )
Applications	WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	104kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human GANC/Neutral alphaglucosidase C
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: A key enzyme in glycogen degradation and metabolism, GANC (glucosidase, α neutral C) is a 914 amino acid protein with α-glucosidase activity that belongs to the glycosyl hydrolase 31 family and hydrolyzes non-reducing, terminal 1,4-linked α-D-glucose residues and releases α-D-glucose. The gene encoding GANC maps to human chromosome 15q15.1, a region associated with susceptibility to non-insulin-dependent (type 2) diabetes mellitus, a disease characterized by high blood glucose levels. Human chromosome 15 houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes. Function: Has alpha-glucosidase activity. Similarity: Belongs to the glycosyl hydrolase 31 family. Database links: Entrez Gene: 2595 Human Omim: 104180 Human SwissProt: Q8TET4 Human Unigene: 143261 Human Unigene: 730806 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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