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Rabbit Anti-C3Orf34/AP Conjugated antibody
Rabbit Anti-C3Orf34/AP Conjugated antibody
Chromosome 3 open reading frame 34; HSD5; LOC84984; MGC14126; CEP19_HUMAN.
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  • NO.:SL15175R-AP
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Mouse,(predicted: Human,Rat,Chicken,Dog,Pig,Cow,Horse,)
    Applications:IHC-P IHC-F ICC
    concentration:1mg/ml
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Details

Product Name Anti-C3Orf34/AP
Chinese Name 碱性磷酸酶(AP)标记的3号染色体开放阅读框34抗体
Alias Chromosome 3 open reading frame 34; HSD5; LOC84984; MGC14126; CEP19_HUMAN.  
Research Area Tumour  Cell biology  immunology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Mouse,  (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Horse, )
Applications IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 19kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human C3Orf34
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
C3orf34 (chromosome 3 open reading frame 34), also known as MGC14126, is a 163 amino acid protein encoded by a gene that maps to human chromosome 3q29. Chromosome 3 is made up of approximately 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3.

Subcellular Location:
Cytoplasm, cytoskeleton, centrosome, centriole. Cytoplasm, cytoskeleton, spindle pole. Note=Associates with the mother centriole in early interphase. Localizes to spindle poles during mitosis, and to distinct foci oriented.

Similarity:
Belongs to the CEP19 family.

Database links:

Entrez Gene: 84984 Human

SwissProt: Q96LK0 Human

SwissProt: Q9CQA8 Mouse

SwissProt: Q9QZX9 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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