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Rabbit Anti-Connexin-36/AP Conjugated antibody
Rabbit Anti-Connexin-36/AP Conjugated antibody
Connexin 36; CX36; Gap junction protein alpha 9; gap junction protein, alpha 9, 36kDa; GJA9; MGC138315; MGC138319; CXD2_HUMAN.
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  • NO.:SL1266R-AP
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Guinea Pig,)
    Applications:WB
    concentration:1mg/ml
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Product Name Anti-Connexin-36/AP
Chinese Name 碱性磷酸酶(AP)标记的间隙连接蛋白36抗体
Alias Connexin 36; CX36; Gap junction protein alpha 9; gap junction protein, alpha 9, 36kDa; GJA9; MGC138315; MGC138319; CXD2_HUMAN.  
Research Area Neurobiology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, )
Applications WB=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 36kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human Connexin-36
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
This gene encodes a member of the connexin protein family. Connexins are gap junction proteins which are arranged in groups of 6 around a central pore to form a connexon, a component of the gap junction intercellular channel. The channels formed by this protein allow cationic molecule exchange between human beta cells and may function in the regulation of insulin secretion. [provided by RefSeq, Oct 2012]

Function:
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.

Subunit:
A connexon is composed of a hexamer of connexins.

Subcellular Location:
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.

Tissue Specificity:
Highly expressed in neurons.

Similarity:
Highly expressed in neurons.
Belongs to the connexin family. Delta-type subfamily.

Database links:

Entrez Gene: 395273 Chicken

Entrez Gene: 282577 Cow

Entrez Gene: 57369 Human

Entrez Gene: 14617 Mouse

Entrez Gene: 50564 Rat

Entrez Gene: 378444 Zebrafish

Omim: 607058 Human

SwissProt: Q866T7 Cow

SwissProt: Q9UKL4 Human

SwissProt: O54851 Mouse

SwissProt: Q6PDP3 Mouse

SwissProt: O70610 Rat

Unigene: 283816 Human

Unigene: 389394 Mouse

Unigene: 9904 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

间隙连接是神经系统构成电突触的结构基础,参与调控神经冲动纤毫传递和复杂神经网络的整合,而Cx36是唯一一个在神经系统中优先表达的Cx,因此成为电生理研究主要蛋白。

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