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Rabbit Anti-FSTL1/AP Conjugated antibody
Rabbit Anti-FSTL1/AP Conjugated antibody
FSTL1; TSC-36; Follistatin like 1; Follistatin related protein; Follistatin-like protein 1; Follistatin-related protein 1; FRP; FSL1; FSTL1; FSTL1_HUMAN.
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  • NO.:SL6050R-AP
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Chicken,Dog,Cow,Horse,Rabbit,)
    Applications:WB IHC-P IHC-F
    concentration:1mg/ml
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Details

Product Name Anti-FSTL1/AP
Chinese Name 碱性磷酸酶(AP)标记的卵泡相关蛋白1
Alias FSTL1; TSC-36; Follistatin like 1; Follistatin related protein; Follistatin-like protein 1; Follistatin-related protein 1; FRP; FSL1; FSTL1; FSTL1_HUMAN.  
Research Area Cardiovascular  Cell biology  Cyclin  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, )
Applications WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 34kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human FSTL1/FRP
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
TSC-36 is a secreted extracellular glycoprotein. The amino acid sequence of TSC-36 is similar to follistatin, an inhibitor of activin, as it contains a follistatin module. TSC-36 is a heparin-binding protein suggested to have a role in the negative regulation of cellular growth, as its expression is induced in response to TGF-b1. In addition, TSC-36 is not found in small cell lung cancer (SCLC) cells, a highly aggressive neoplasm, but is detected in some non-small cell lung cancer (NSCLC) cells, a moderately aggressive neoplasm.. May modulate the action of some growth factors on cell proliferation and differentiation. Binds heparin.

Function:
May modulate the action of some growth factors on cell proliferation and differentiation. Binds heparin.

Subunit:
Interacts with SCN10A.

Subcellular Location:
Secreted.

Tissue Specificity:
Overexpressed in synovial tissues from rheumatoid arthritis.

Similarity:
Contains 2 EF-hand domains.
Contains 1 follistatin-like domain.
Contains 1 Kazal-like domain.
Contains 1 VWFC domain.

Database links:
 

 

Entrez Gene: 534482 Cow

Entrez Gene: 11167 Human

Entrez Gene: 14314 Mouse

Entrez Gene: 79210 Rat

Omim: 605547 Human

SwissProt: Q58D84 Cow

SwissProt: Q12841 Human

SwissProt: Q62356 Mouse

SwissProt: Q62632 Rat

Unigene: 269512 Human

Unigene: 182434 Mouse

Unigene: 95652 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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