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Rabbit Anti-LRRC15/AP Conjugated antibody
Rabbit Anti-LRRC15/AP Conjugated antibody
Leucine-rich repeat-containing protein 15; LIB; LRC15_HUMAN.
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  • NO.:SL6815R-AP
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,)
    Applications:WB IHC-P IHC-F ICC
    concentration:1mg/ml
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Details

Product Name Anti-LRRC15/AP
Chinese Name 碱性磷酸酶(AP)标记的富含亮氨酸重复蛋白15抗体
Alias Leucine-rich repeat-containing protein 15; LIB; LRC15_HUMAN.  
Research Area Tumour  Neurobiology  Signal transduction  TumourCell biologyMaker  Alzheimer's  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 62kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human LRRC15
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
LRRC15 may contribute to regulation of cell-matrix adhesion interactions with respect to astrocyte recruitment around senile plaques in Alzheimer's disease brain. LRRC15 is induced by EWS-WT1(+KTS) in the tumor DSRCT and may play a role in cellular invasion.

Function:
LRRC15 may contribute to regulation of cell-matrix adhesion interactions with respect to astrocyte recruitment around senile plaques in Alzheimer's disease brain. LRRC15 is induced by EWS-WT1(+KTS) in the tumor DSRCT and may play a role in cellular invasion.

Subcellular Location:
Membrane; Single-pass type I membrane protein (Potential)

Tissue Specificity:
Brain and placenta.

Similarity:
Contains 15 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain.

Database links:
UniProtKB/Swiss-Prot: Q8TF66.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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