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Product Name Anti-Bcl 2 like 13 protein/AP Chinese Name 碱性磷酸酶(AP)标记的Bcl2样凋亡蛋白13抗体 Alias Apoptosis facilitator; Bcl 2 like 13; Bcl 2 like 13 protein; BCL2 like 13 apoptosis facilitator; BCL2 like 13; Bcl2 like 13 protein; BCL2L13; MIL 1; MIL1; MIL1 protein; Protein Mil1; B2L13_HUMAN. Research Area Cell biology Apoptosis Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Chicken, Dog, Pig, Horse, Rabbit, ) Applications WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 53kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Bcl rambo/Bcl 2 like 13 protein Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Bcl rambo shares common structural characteristics with other members of the anti-apoptotic Bcl2 family members, but differs from them at its C-terminus, where a 250 amino acid sequence preceeds the membrane anchor region. It also differs from other pro-apoptotic Bcl-2 family members in that its membrane anchor C-terminus region is responsible for its apoptotic activity, not its Bcl-2 homology motifs. Bcl rambo may promote the activation of caspase-3 and apoptosis.
Function:
May promote the activation of caspase-3 and apoptosis.
Subunit:
Monomer
Subcellular Location:
Isoform 2: Mitochondrion membrane; Single-pass membrane protein (Potential). Nucleus.
Isoform 1: Nucleus
Tissue Specificity:
Ubiquitous, with the highest levels of expression in heart, placenta and pancreas.
Similarity:
Belongs to the Bcl-2 family.
Database links:Entrez Gene: 23786 Human
Entrez Gene: 94044 Mouse
SwissProt: Q9BXK5 Human
SwissProt: P59017 Mouse
Unigene: 631672 Human
Unigene: 27990 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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