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Rabbit Anti-ICAM4/AP Conjugated antibody
Rabbit Anti-ICAM4/AP Conjugated antibody
CD242; CD242 antigen; ICAM-4; Icam4; ICAM4_HUMAN; Intercellular adhesion molecule 4; Landsteiner Wiener blood group glycoprotein; Landsteiner-Wiener blood group glycoprotein; LW; LW blood group protein.
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  • NO.:SL7637R-AP
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,)
    Applications:WB IHC-P IHC-F
    concentration:1mg/ml
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Details

Product Name Anti-ICAM4/AP
Chinese Name 碱性磷酸酶(AP)标记的细胞间粘附分子4抗体
Alias CD242; CD242 antigen; ICAM-4; Icam4; ICAM4_HUMAN; Intercellular adhesion molecule 4; Landsteiner Wiener blood group glycoprotein; Landsteiner-Wiener blood group glycoprotein; LW; LW blood group protein.  
Research Area Cardiovascular  Cell biology  immunology  Signal transduction  Apoptosis  Cell adhesion molecule  Cytoskeleton  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, )
Applications WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 27kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human ICAM4 (75-117aa)
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM4 is also a ligand for alpha-4/beta-1 and alpha-V integrins.

Function:
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM4 is also a ligand for alpha-4/beta-1 and alpha-V integrins.

Subcellular Location:
Isoform Long: Cell membrane; Single-pass type I membrane protein. Isoform Short: Secreted.

Tissue Specificity:
Erythrocytes.

Post-translational modifications:
N- and O-glycosylated.

Similarity:
Belongs to the immunoglobulin superfamily. ICAM family.
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.

Database links:

Entrez Gene: 3386 Human

Entrez Gene: 78369 Mouse

Entrez Gene: 298702 Rat

Omim: 614088 Human

SwissProt: Q14773 Human

SwissProt: Q9ERM2 Mouse

Unigene: 706750 Human

Unigene: 30220 Mouse

Unigene: 222410 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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