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Rabbit Anti-GTF2B/AP Conjugated antibody
Rabbit Anti-GTF2B/AP Conjugated antibody
TFIIB; General transcription factor IIB; General transcription factor TFIIB; GTF2B; RNA polymerase II transcription factor IIB; S300 II; S300-II; TF IIB; TF2B; TF2B_HUMAN; Transcription initiation factor IIB.
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  • NO.:SL8168R-AP
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Cow,Horse,Rabbit,)
    Applications:WB IHC-P IHC-F
    concentration:1mg/ml
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Product Name Anti-GTF2B/AP
Chinese Name 碱性磷酸酶(AP)标记的通用转录因子GTF2B抗体
Alias TFIIB; General transcription factor IIB; General transcription factor TFIIB; GTF2B; RNA polymerase II transcription factor IIB; S300 II; S300-II; TF IIB; TF2B; TF2B_HUMAN; Transcription initiation factor IIB.  
Research Area Cell biology  immunology  transcriptional regulatory factor  Epigenetics  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Cow, Horse, Rabbit, )
Applications WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 35kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human GTF2B corresponding to amino acids 131-180.
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II.

Function:
General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II.

Subunit:
Associates with TFIID-IIA (DA complex) to form TFIID-IIA-IIB (DAB-complex) which is then recognized by polymerase II. Interacts with the transcription elongation factor TCEA2. Interacts with HIV-1 Vpr. Interacts with GPBP1 (By similarity). Interacts with Epstein-Barr virus EBNA2.

Subcellular Location:
Nucleus

Similarity:
Belongs to the TFIIB family.
Contains 1 TFIIB-type zinc finger.

Database links:
UniProtKB/Swiss-Prot: Q00403.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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