Product Name	Anti-BPIL3/AP
Chinese Name	碱性磷酸酶（AP）标记的杀菌/通透性增加蛋白样3抗体
Alias	Bactericidal/permeability increasing protein like 3; BPIL 3; BPIL-3; LPLUNC6; OTTHUMP00000030617.
Research Area	Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Pig, Cow, Horse, Sheep, )
Applications	WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	48kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human BPIL3
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: Members of the bactericidal/permeability-increasing protein family have antimicrobial properties and bind lipophilic substances, therefore targeting gram-negative bacteria. The bactericidal permeability increasing protein (BPI) is an antibacterial and endotoxin-neutralizing molecule that is abundant in the granules of polymorphonuclear leukocytes (neutrophil granules). Sharing structural and sequence homologies with BPI, BPIL3 (Bactericidal/permeability-increasing protein-like 3) is a 453 amino acid secreted protein that contains the family’s common conserved feature of two cysteine residues that are critical for protein function. While BPIL3 is primarily expressed at low levels in tonsils, it has been found to be upregulated in hypertrophic tonsil tissue, suggesting that it may play a role in the pathogenesis of inflamed disease tissue. Subcellular Location: Secreted (By similarity). Tissue Specificity: Detected at very low levels in normal tonsils, and at higher levels in hypertrophic tonsils. Similarity: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. Database links: UniProtKB/Swiss-Prot: Q8NFQ5.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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