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Product Name Anti-CMTM2/AP Chinese Name 碱性磷酸酶(AP)标记的趋化素样因子超家族成员2抗体 Alias Chemokine like factor super family 2; Chemokine like factor superfamily 2; Chemokine like factor superfamily member 2; CKLF like MARVEL transmembrane domain containing; CKLF like MARVEL transmembrane domain containing protein 2; CKLFSF2; CMTM 2; CMTM2; CMTM-2; CLF2B_MOUSE. Research Area Tumour Cell biology immunology Developmental biology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Mouse, Rat, ) Applications WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 24kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from mo CKLFSF2/CMTM2 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
This gene belongs to the chemokine-like factor gene superfamily, a novel family that links the chemokine and the transmembrane 4 superfamilies of signaling molecules. The protein encoded by this gene may play an important role in testicular development.
Subcellular Location:
Membrane; Multi pass membrane protein
Tissue Specificity:
Highly expressed in testis.
Similarity:
Belongs to the chemokine-like factor family.
Contains 1 MARVEL domain.
Database links:
Entrez Gene: 520499 Cow Entrez Gene: 479694 Dog Entrez Gene: 146225 Human Omim: 607885 Human SwissProt: Q8TAZ6 Human Unigene: 195685 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
CKLFSF2蛋白特异性的表达于减数分裂及分裂后的各级生精细胞中,它定位于高尔基体周围的内质网上,而且和生精功能损害密切相关。 CKLFSF2可能在减数分裂及精子生成的过程中发挥重要作用,并可能与内质网的囊泡转运和膜定位过程相关联。
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