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Rabbit Anti-CPEB3/AP Conjugated antibody
Rabbit Anti-CPEB3/AP Conjugated antibody
CPE-binding protein 3; CPE-BP3; CPEB 3; Cpeb3; CPEB3_HUMAN; Cytoplasmic polyadenylation element binding protein 3; Cytoplasmic polyadenylation element-binding protein 3; hCPEB-3; KIAA0940.
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  • NO.:SL11340R-AP
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,)
    Applications:WB IHC-P IHC-F ICC
    concentration:1mg/ml
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Details

Product Name Anti-CPEB3/AP
Chinese Name 碱性磷酸酶(AP)标记的细胞质多聚腺苷酸Binding protein3抗体
Alias CPE-binding protein 3; CPE-BP3; CPEB 3; Cpeb3; CPEB3_HUMAN; Cytoplasmic polyadenylation element binding protein 3; Cytoplasmic polyadenylation element-binding protein 3; hCPEB-3; KIAA0940.  
Research Area Cell biology  Neurobiology  Cyclin  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 76kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human CPEB3
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
The regulated translation of messenger RNA is essential for cell-cycle progression, establishment of the body plan during early development and modulation of key activities in the central nervous system. Cytoplasmic polyadenylation, one mechanism of controlling translation, is driven by cytoplasmic polyadenylation element binding proteins, called CPEBs. CPEB3 (cytoplasmic polyadenylation element binding protein 3) is a 698 amino acid protein that contains two RNA recognition motif (RRM) domains and, like other CPEB proteins, may play a role in the maturation of the central nervous system. CPEB3 exists as multiple alternatively spliced isoforms that are encoded by a gene which maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome.

Similarity:
Belongs to the RRM CPEB family.
Contains 2 RRM (RNA recognition motif) domains.

Database links:

Entrez Gene: 22849 Human

Entrez Gene: 208922 Mouse

SwissProt: Q8NE35 Human

SwissProt: Q7TN99 Mouse

Unigene: 131683 Human

Unigene: 701732 Human

Unigene: 371677 Mouse

Unigene: 391176 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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