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Rabbit Anti-CD134/APC Conjugated antibody
Rabbit Anti-CD134/APC Conjugated antibody
Tumor necrosis factor receptor superfamily member 4; ACT 35; ACT35; ACT35 antigen; CD 134; CD134 antigen; Lymphoid activation antigene ACT35; OX 40; OX40; OX40 antigen; OX40 cell surface antigen; OX40 homologue; OX40L receptor; TAX transcriptionally activ
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  • NO.:SL23800R-APC
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,)
    Applications:ICC IF
    concentration:1mg/ml
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Product Name Anti-CD134/APC
Chinese Name APC标记的CD134抗体
Alias Tumor necrosis factor receptor superfamily member 4; ACT 35; ACT35; ACT35 antigen; CD 134; CD134 antigen; Lymphoid activation antigene ACT35; OX 40; OX40; OX40 antigen; OX40 cell surface antigen; OX40 homologue; OX40L receptor; TAX transcriptionally activated glycoprotein 1 receptor; TNFRSF 4; TNFRSF4.  
Research Area
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, )
Applications ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 27kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human CD134
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.05M PB, pH 7.5.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008].

Function:
Receptor for TNFSF4/OX40L/GP34.

Subunit:
Interacts with TRAF2, TRAF3 and TRAF5.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Similarity:
Contains 4 TNFR-Cys repeats.

Database links:
Entrez Gene: 7293 Human

Omim: 600315 Human

SwissProt: P43489 Human

Unigene: 129780 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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