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Product Name Anti-SNRK/APC Chinese Name APC标记的SNF相关丝氨酸/苏氨酸蛋白激酶抗体 Alias DKFZp779A1866; FLJ20224; HSNFRK; KIAA0096; SNF related kinase; SNF related serine/threonine protein kinase; SNF-related serine/threonine-protein kinase; SNF1 related kinase; SNF1-related kinase; SNFRK; Snrk; SNRK_HUMAN. Research Area Cardiovascular Cell biology Signal transduction Kinases and Phosphatases Immunogen Species Rabbit Clonality Polyclonal React Species Human, (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, Guinea Pig, ) Applications
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 84kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SNRK Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
SNRK is a member of the sucrose nonfermenting (SNF)-related kinase family of serine/threonine kinases (Kertesz et al., 2002 [PubMed 12234663]).[supplied by OMIM, Apr 2009]
Function:
May play a role in hematopoietic cell proliferation or differentiation. Potential mediator of neuronal apoptosis.
Subcellular Location:
Nucleus.
Tissue Specificity:
Expressed in hematopoietic progenitor cells and leukemic cell lines. Weakly expressed in the testis.
Post-translational modifications:
Autophosphorylated.
Similarity:
Belongs to the protein kinase superfamily.
CAMK Ser/Thr protein kinase family.
Contains 1 protein kinase domain.
Contains 1 UBA domain.
Database links:
Entrez Gene: 54861 Human
Entrez Gene: 20623 Mouse
SwissProt: Q9NRH2 Human
SwissProt: Q8VDU5 Mouse
Unigene: 476052 Human
Unigene: 257989 Mouse
Unigene: 10245 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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