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Product Name Anti-PPIL4/APC Chinese Name APC标记的亲环素蛋白ppil4抗体 Alias Cyclophilin type peptidyl prolyl cis trans isomerase; Cyclophilin-like protein PPIL4; HDCME13P; Peptidyl-prolyl cis-trans isomerase-like 4; Peptidylprolyl isomerase (cyclophilin) like 4; PPIase; Ppil4; PPIL4_HUMAN; Rotamase; Rotamase PPIL4; serologically defined breast cancer antigen NY-BR-18. Research Area Cell biology Signal transduction Transporter Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 57kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human PPIL4 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
This gene is a member of the cyclophilin family of peptidylprolyl isomerases. The cyclophilins are a highly conserved family, members of which play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. [provided by RefSeq, Jul 2008]
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Subcellular Location:
Nucleus.
Tissue Specificity:
Abundantly expressed in kidney but has a ubiquitously low expression pattern in other adult tissues.
Similarity:
Belongs to the cyclophilin-type PPIase family.
PPIL4 subfamily.
Contains 1 PPIase cyclophilin-type domain.
Contains 1 RRM (RNA recognition motif) domain.
Database links:Entrez Gene: 85313 Human
Entrez Gene: 67418 Mouse
Omim: 607609 Human
SwissProt: Q8WUA2 Human
SwissProt: Q9CXG3 Mouse
Unigene: 593411 Human
Unigene: 38927 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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