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Product Name Anti-MFAP4/APC Chinese Name APC标记的微丝相关蛋白4抗体 Alias MFAP4; MFAP4_HUMAN; Microfibril-associated glycoprotein 4; Microfibrillar associated protein 4. Research Area Cell biology immunology Signal transduction Extracellular matrix Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 26kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human MFAP4 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
This gene encodes a protein with similarity to a bovine microfibril-associated protein. The protein has binding specificities for both collagen and carbohydrate. It is thought to be an extracellular matrix protein which is involved in cell adhesion or intercellular interactions. The gene is located within the Smith-Magenis syndrome region. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
Function:
Could be involved in calcium-dependent cell adhesion or intercellular interactions.
Subcellular Location:
Secreted; extracellular space; extracellular matrix.
DISEASE:
MFAP4 is deleted in the Smith-Magenis syndrome (SMS) [MIM:182290].
Similarity:
Contains 1 fibrinogen C-terminal domain.
Database links:Entrez Gene: 4239 Human
Entrez Gene: 76293 Mouse
Omim: 600596 Human
SwissProt: P55083 Human
SwissProt: Q9D1H9 Mouse
Unigene: 296049 Human
Unigene: 272278 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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