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Product Name Anti-MANSC1/APC Chinese Name APC标记的MANSC1蛋白抗体 Alias 9130403P13Rik; FLJ10298; LOH12CR3; Loss of heterozygosity 12 chromosomal region 3 protein; MANS1_HUMAN; MANSC domain containing 1; MANSC domain-containing protein 1; MANSC1. Research Area Cell biology immunology The cell membrane蛋白 Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, Dog, Cow, Horse, Sheep, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 44kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human MANSC1 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
MANSC1 is a 414 amino acid single-pass membrane protein. Expressed throughout the body, MANSC1 contains one MANSC domain and is encoded by a gene that is located on chromosome 12. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction.
Subcellular Location:
Membrane.
Tissue Specificity:
Widely expressed.
Similarity:
Contains 1 MANSC domain.
Database links:Entrez Gene: 54682 Human
Entrez Gene: 67729 Mouse
SwissProt: Q9H8J5 Human
SwissProt: Q9CR33 Mouse
Unigene: 591145 Human
Unigene: 57648 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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