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Product Name Anti-TRPV2/APC Chinese Name APC标记的辣椒素受体样蛋白1抗体 Alias Osm 9 like TRP channel 2; Osm-9-like TRP channel 2; OTRPC2; Sac2b; Stretch activated channel 2B; Transient receptor potential cation channel subfamily V member 2; TrpV2; TRPV2_HUMAN; Vanilloid receptor like protein 1; Vanilloid receptor-like protein 1; VRL 1; VRL; VRL-1; VRL1. Research Area Immunogen Species Rabbit Clonality Polyclonal React Species Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 86kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human TRPV2 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH.
Function:
Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH.
Subunit:
Homotetramer.
Subcellular Location:
Cell membrane; Multi-pass membrane protein. Cytoplasm. Melanosome.
Post-translational modifications:
N-glycosylated.
Phosphorylated by PKA.
Similarity:
Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV2 sub-subfamily.
Contains 6 ANK repeats.
Database links:Entrez Gene: 51393 Human
Omim: 606676 Human
SwissProt: Q9Y5S1 Human
Unigene: 279746 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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