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Product Name Anti-KCNK16/APC Chinese Name APC标记的钾离子Channel protein16抗体 Alias 2P domain potassium channel Talk 1; pancreatic potassium channel Talk 1; potassium channel subfamily K member 16; TALK 1; KCNKG_HUMAN; TALK1; TWIK related alkaline pH activated K(+) channel 1. Research Area Tumour Cell biology immunology Neurobiology Channel protein Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 34kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human KCNK16 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
The protein encoded by the KCNK16 gene belongs to a family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. This gene is activated at alkaline pH and is expressed predominantly in the pancreas. Several alternatively spliced transcript variants encoding different isoforms have been identified.
Function:
Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents.
Subunit:
Homodimer (Potential).
Subcellular Location:
Membrane; Multi-pass membrane protein
Similarity:
Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
Database links:Entrez Gene: 83795 Human
Omim: 607369 Human
SwissProt: Q96T55 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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