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Product Name Anti-GTPBP1/APC Chinese Name APC标记的G蛋白Binding protein1抗体 Alias G protein 1; GP 1; GTPB1_HUMAN; GP1; GTP binding protein 1. Research Area Signal transduction transcriptional regulatory factor Immunogen Species Rabbit Clonality Polyclonal React Species Rat, (predicted: Human, Mouse, Chicken, Dog, Cow, Horse, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 72kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human GTPBP1 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
This gene is upregulated by interferon-gamma and encodes a protein that is a member of the AGP11/GTPBP1 family of GTP-binding proteins. A structurally similar protein has been found in mouse, where disruption of the gene for that protein had no observable phenotype. [provided by RefSeq, Jul 2008]
Function:
The GTPBP1 gene is upregulated by interferon gamma and the protein is a member of the AGP11/GTPBP1 family of GTP binding proteins. A structurally similar protein has been found in mouse, where disruption of the gene for that protein had no observable phenotype. This gene is upregulated by interferon gamma and encodes a protein that is a member of the AGP11/GTPBP1 family of GTP binding proteins. A structurally similar protein has been found in mouse, where disruption of the gene for that protein had no observable phenotype.
Subunit:
Interacts with EXOSC2/RRP4, EXOSC3/RRP40, EXOSC5/RRP46, HNRNPD, HNRNPR and SYNCRIP. Identified in a complex with AANAT mRNA, but does not bind mRNA by itself (By similarity).
Subcellular Location:
Cytoplasm (By similarity).
Similarity:
Belongs to the GTPBP1 GTP-binding protein family.
Database links:Entrez Gene: 9567 Human
Entrez Gene: 14904 Mouse
Omim: 602245 Human
SwissProt: O00178 Human
SwissProt: O08582 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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