Product Name	Anti-CEACAM7/APC
Chinese Name	APC标记的癌胚抗原相关Cell adhesion molecule7抗体
Alias	Carcinoembryonic antigen CGM 2; Carcinoembryonic antigen CGM2; Carcinoembryonic antigen gene family member 2; Carcinoembryonic antigen related cell adhesion molecule 7; Carcinoembryonic antigen-related cell adhesion molecule 7; CEA; CEACAM 7; CEACAM7; CEAM7_HUMAN; CGM 2; CGM2.
Research Area	Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, )
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	26kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human CEACAM7
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: Carcinoembryonic antigen (CEA) is one of the most commonly used tumor markers in serum immunoassay determinations of carcinoma. Members of the CEA family contain a single N domain, with structural homology to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. CEACAM7, also referred to as CEA gene-family member 2 (CGM2), is a member of the CEA family that is expressed in normal colorectal epithelia but is downregulated in colorectal cancers, suggesting that it may play a role in tumorigenesis. CECAM7 is expressed on the apical surface of highly differentiated epithelial cells in the colorectal mucosa as well as on isolated ductal epithelial cells within the pancreas. CECAM7 may play an important role in epithelial-microbial interactions. CD66a, a biliary glycoprotein, interacts with CEACAM7. Subcellular Location: Cell membrane. Tissue Specificity: Strongly down-regulated in colonic adenocarcinomas. Similarity: Belongs to the immunoglobulin superfamily. CEA family. Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 1 Ig-like V-type (immunoglobulin-like) domain. Database links: Entrez Gene: 1087 Human SwissProt: Q14002 Human Unigene: 74466 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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