Product Name	Anti-GABRR2/APC
Chinese Name	APC标记的G氨基丁酸A型受体rho2 /GABAA Rρ2抗体
Alias	GABA receptor Rho 2 subunit; GABA(A) receptor; GABA(A) receptor subunit rho-2; GABA(C) receptor; GABRR 2; Gamma aminobutyric acid receptor rho 2 subunit [Precursor]; Gamma-aminobutyric acid (GABA) A receptor, rho 2; Gamma-aminobutyric acid receptor subunit rho-2; Rho 2 GABA receptor; GBRR2_HUMAN.
Research Area	Neurobiology  Channel protein  The cell membrane受体  G protein-coupled receptor  G protein signal
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Zebrafish, Sheep, )
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	52kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human GABRR2
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. The protein encoded by this gene is a member of the rho subunit family and is a component of the GABA receptor complex. [provided by RefSeq, Jul 2008] Function: GABA is the major inhibitory neurotransmitter in the vertebrate brain and mediates neuronal inhibition by binding to the gaba/benzodiazepine receptors and opening an integral chloride channel. GABRR2 is a member of the rho subunit family of GABA receptors and could play a role in retinal neurotransmission. Subunit: Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Interacts with SQSTM1 Subcellular Location: Cell junction > synapse > postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Similarity: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRR2 sub-subfamily. Database links: Entrez Gene: 2570 Human Entrez Gene: 14409 Mouse Entrez Gene: 29695 Rat Entrez Gene: 522099 Cow Omim: 137162 Human SwissProt: Q0II76 Cow SwissProt: P28476 Human SwissProt: P56476 Mouse Unigene: 99927 Human Unigene: 6227 Mouse Unigene: 48659 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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