Product Name	Anti-CCR9/APC
Chinese Name	APC标记的细胞表面Chemokine受体9抗体
Alias	CCR-9; C C chemokine receptor D6; C C chemokine receptor type 9; C C CKR 9; CC Chemokine receptor CCR10; CC CKR 9; CCBP2; CCCKR9; CCR 9; CCR9; CDw199; CDw199 antigen; Chemokine C C motif receptor 9; Chemokine CC Motif Receptor 9; Chemokine receptor CCR 9; Chemokine-binding protein D6; CMKBR9; G protein coupled receptor 28; GPR 28; GPR 9 6; GPR28; GPR96; CCR9_HUMA.
Research Area	Tumour  immunology  transcriptional regulatory factor
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, Dog, Cow, Horse, Rabbit, Sheep, )
Applications	IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	40kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human CCR9 (107-127aa)
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: The protein encoded by this gene is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein coupled receptors. Chemokines and their receptors are key regulators of the thymocytes migration and maturation in normal and inflammation conditions. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. The specific ligand of this receptor is CCL25. It has been found that this gene is differentially expressed by T lymphocytes of small intestine and colon, suggested a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes. Two alternatively spliced transcript variants have been described. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Highly expressed in the thymus and low in lymph nodes and spleen. Similarity: Belongs to the G-protein coupled receptor 1 family. Database links: Entrez Gene: 10803 Human Entrez Gene: 12769 Mouse Entrez Gene: 282832 Rat Omim: 604738 Human SwissProt: P51686 Human SwissProt: Q9WUT7 Mouse Unigene: 225946 Human Unigene: 91140 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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