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Product Name Anti-ATP4B/APC Chinese Name APC标记的氢钾ATP酶Channel protein抗体 Alias Gastric H(+)/K(+) ATPase subunit beta; H+K+ ATPase; ATP4B; ATP6B; ATPase H+/K+ exchanging beta polypeptide; ATPase H+/K+ transporting beta polypeptide;Gastric H K ATPase catalytic subunit; Gastric H+/K+ ATPase beta subunit; Gastric hydrogen potassium ATPase; Gastric hydrogen potassium ATPase beta; Hydrogen/potassium exchanging ATPase 4B; Potassium transporting ATPase beta chain; Potassium transporting ATPase subunit beta; Proton pump; Proton pump beta chain; ATP4B_HUMAN. Research Area Cell biology immunology transcriptional regulatory factor Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Rabbit, ) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 33kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human ATP4B Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
The protein encoded by this gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes the beta subunit of the gastric H+, K+-ATPase. [provided by RefSeq, Jul 2008]
Function:
Required for stabilization and maturation of the catalytic proton pump alpha subunit and may also involved in cell adhesion and establishing epithelial cell polarity.
Subunit:
Composed of two subunits: alpha (catalytic) and beta.
Subcellular Location:
Cell membrane
Tissue Specificity:
Expressed at highest levels in heart, skeletal
Similarity:
Belongs to the X(+)/potassium ATPases subunit beta family.
Database links:Entrez Gene: 496 Human
Entrez Gene: 11945 Mouse
Omim: 137217 Human
SwissProt: P51164 Human
SwissProt: P50992 Mouse
SwissProt: P18597 Rabbit
Unigene: 434202 Human
Unigene: 154039 Mouse
Unigene: 10033 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Username | Quantity | bought time |
Ca*** | 1 | 2024-09-05 |
Sa*** | 1 | 2023-11-30 |
Ab*** | 2 | 2023-11-18 |
Sa*** | 2 | 2023-11-10 |
Ga*** | 1 | 2023-07-21 |
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