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Rabbit Anti-LETMD1/APC Conjugated antibody
Rabbit Anti-LETMD1/APC Conjugated antibody
LETM1 domain-containing protein 1; Cervical cancer 1 proto-oncogene protein p40; Cervical cancer proto-oncogene 2 protein; HCCR-1; HCRR-2; LTMD1_HUMAN; HCCR 2; HCCR2.
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  • NO.:SL5937R-APC
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Cow,Horse,)
    Applications:IF
    concentration:1mg/ml
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Product Name Anti-LETMD1/APC
Chinese Name APC标记的宫颈癌原癌基因2抗体
Alias LETM1 domain-containing protein 1; Cervical cancer 1 proto-oncogene protein p40; Cervical cancer proto-oncogene 2 protein; HCCR-1; HCRR-2; LTMD1_HUMAN; HCCR 2; HCCR2.  
Research Area Tumour  immunology  TumourCell biologyMaker  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Cow, Horse, )
Applications IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 40kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human HCCR2/LETMD1
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
This gene encodes a mitochondrial outer membrane protein. It has a potential role in tumorigenesis, which may result from negative regulation of the p53 tumor suppressor gene. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Aug 2011].

Function:
Involved in tumorigenesis and may function as a negative regulator of the p53/TP53.

Subunit:
Interacts with BRI3BP.

Subcellular Location:
Mitochondrion outer membrane; Single-pass membrane protein.

Tissue Specificity:
Kidney, liver, skeletal muscle, heart and brain. Overexpressed in various tumors including leukemia, lymphoma, and carcinomas of the breast, kidney, ovary, stomach, colon and uterine cervix.

Similarity:
Contains 1 LETM1 domain.

Database links:
UniProtKB/Swiss-Prot: Q6P1Q0

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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