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Product Name Anti-CD161c/APC Chinese Name APC标记的CD161c抗体 Alias CD161 antigen like family member C; CD161 antigen-like family member C; CD161c; Killer cell lectin like receptor subfamily A member 1C; Killer cell lectin like receptor subfamily B member 1C; Klrb1c; Ly55c; Lymphocyte antigen 55c; Ly59; Lymphocyte antigen 59; Natural killer cell surface protein P1 40; Natural killer cell surface protein P1-40; Ly-55c; NK1.1 alloantigen; NKR P1.9; NKR P1C; NKRP1 40; NKRP1; NKRP1.9; Nkrp1-c; NKRP1C; NK-1.1; Nk-1.2; NK-RP1; NK1.1; NKR-P1; Nkrp1c; NKR-P1.9; NKR-P1C; KLRB1_MOUSE. Research Area Tumour Signal transduction The cell membrane受体 Natural killer cells t-lymphocyte epithelial cells Immunogen Species Rabbit Clonality Polyclonal React Species Human, Mouse, (predicted: Rat, ) Applications
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 25kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from mouse CD161/NK1.1 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
NK1.1, a member of the NKRPI family of cell surface receptors, is a type II integral membrane protein with a C type lectin domain. It is expressed as a disulfide linked homodimer on all NK cells, as well as subsets of thymocytes and peripheral T lymphocytes in selected strains of mice (e.g., C57/BL6, FVB/N, NZB; but not A, AKR, BALB/c, CBA/J, C3H, C57BR, C58, DBA/1, DBA/2, SJL, 129). NK1.1 mediates cellular activation and differentiation, and is thought to have a particular role in generating Th2 cells.
Subunit:
Homodimer; disulfide-linked. Interacts with acid phingomyelinase/SMPD1.
Subcellular Location:
Membrane; Single-pass type II membrane protein (Potential).
Tissue Specificity:
Expressed in a subset of NK cells predominantly in intestinal epithelium and liver. Detected in peripheral blood T-cells and preferentially in adult T-cells with a memory antigenic phenotype.
Similarity:
Contains 1 C-type lectin domain.
Database links:Entrez Gene: 3820 Human
Entrez Gene: 100043861 Mouse
Omim: 602890 Human
SwissProt: Q12918 Human
SwissProt: Q0ZUP1 Mouse
Unigene: 169824 Human
Unigene: 66911 Mouse
Unigene: 198693 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Username | Quantity | bought time |
Na*** | 2 | 2024-09-10 |
Ev*** | 1 | 2024-07-24 |
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