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Rabbit Anti-DDIT4L/APC Conjugated antibody
Rabbit Anti-DDIT4L/APC Conjugated antibody
DNA damage inducible transcript 4 like protein; HIF 1 responsive protein RTP801 like; Homolog of mouse SMHS1; Protein regulated in development and DNA damage response 2; REDD 2; REDD2; RTP801L; DDT4L_HUMAN.
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  • NO.:SL6376R-APC
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Human,(predicted: Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,)
    Applications:IF
    concentration:1mg/ml
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Details

Product Name Anti-DDIT4L/APC
Chinese Name APC标记的DNA损伤诱导转录样蛋白4抗体
Alias DNA damage inducible transcript 4 like protein; HIF 1 responsive protein RTP801 like; Homolog of mouse SMHS1; Protein regulated in development and DNA damage response 2; REDD 2; REDD2; RTP801L; DDT4L_HUMAN.  
Research Area Cell biology  immunology  Cyclin  transcriptional regulatory factor  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
Applications IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 22kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human DDIT4L
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
DDIT4L inhibits cell growth by regulating the FRAP1 pathway upstream of the TSC1-TSC2 complex and downstream of AKT1. It is up regulated in atherosclerotic plaques relative to healthy segments of the same artery.

Function:
Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Up-regulated in atherosclerotic plaques relative to healthy segments of the same artery.

Similarity:
Belongs to the DDIT4 family.

Database links:

Entrez Gene: 115265 Human

Entrez Gene: 73284 Mouse

Entrez Gene: 140582 Rat

Omim: 607730 Human

SwissProt: Q96D03 Human

SwissProt: Q8VHZ5 Mouse

SwissProt: Q8VD50 Rat

Unigene: 480378 Human

Unigene: 250841 Mouse

Unigene: 19672 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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