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Product Name Anti-SEZ6/AF647 Chinese Name AF647标记的癫痫相关基因6抗体 Alias Brain-specific receptor-like protein C; BSRP-C; hSEZ-6; Seizure protein 6; Seizure protein 6 homolog; Seizure related gene 6; SEZ-6; Sez6; SEZ6_HUMAN. Research Area Cell biology Neurobiology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 105kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SEZ6 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail Function:
May play a role in cell-cell recognition and in neuronal membrane signaling. Seems to be important for the achievement of the necessary balance between dendrite elongation and branching during the elaboration of a complex dendritic arbor. Involved in the development of appropriate excitatory synaptic connectivity.
Subcellular Location:
Cell membrane. Localized on dendrites and in the synaptic and postsynaptic fraction.
Post-translational modifications:
Glycosylated.
Similarity:
Belongs to the SEZ6 family.
Contains 2 CUB domains.
Contains 5 Sushi (CCP/SCR) domains.
Database links:
Entrez Gene: 124925 Human
Entrez Gene: 20370 Mouse
SwissProt: Q53EL9 Human
SwissProt: Q7TSK2 Mouse
Unigene: 21837 Human
Unigene: 229330 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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