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Product Name Anti-TRIM29 (acetyl K116)/AF647 Chinese Name AF647标记的乙酰化TRIM29蛋白抗体 Alias Ataxia telangiectasia group D associated protein; Ataxia telangiectasia group D-associated protein; ATDC; FLJ36085; TRI29_HUMAN; TRIM 29; TRIM29; Tripartite motif containing 29; Tripartite motif containing protein 29; Tripartite motif protein 29; Tripartite motif protein TRIM29; Tripartite motif-containing protein 29. Product Type Acetylated anti Research Area Cell biology immunology Signal transduction transcriptional regulatory factor Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Pig, Cow, Rabbit, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 66kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated Synthesised acetylpeptide derived from human TRIM29 around the acetylation site of K116 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype. [provided by RefSeq, Jul 2008]
Function:
It is able to complement the radiosensitivity defect of an ataxia telangiectasia (AT) fibroblast cell line.
Subcellular Location:
Cytoplasm. Colocalizes with intermediate filaments.
Tissue Specificity:
Expressed in placenta, prostate and thymus.
Post-translational modifications:
Constitutively phosphorylated by PKC on serine/threonine in A431 cells.
Similarity:
Contains 1 B box-type zinc finger.
Database links:Entrez Gene: 23650 Human
Entrez Gene: 72169 Mouse
Omim: 610658 Human
SwissProt: Q14134 Human
SwissProt: Q8R2Q0 Mouse
Unigene: 504115 Human
Unigene: 273277 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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