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Rabbit Anti-DCBLD2/AF647 Conjugated antibody
Rabbit Anti-DCBLD2/AF647 Conjugated antibody
CLCP1; coagulation factor V/VIII-homology domains protein 1; CUB, LCCL and coagulation factor V/VIII-homology domains protein 1; discoidin CUB and LCCL domain containing 2; Discoidin, CUB and LCCL domain-containing protein 2; endothelial and smooth muscle
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  • NO.:SL5834R-AF647
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Horse,)
    Applications:IF
    concentration:1mg/ml
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Details

Product Name Anti-DCBLD2/AF647
Chinese Name AF647标记的endothelial cells和平滑肌细胞衍生的神经纤毛蛋白抗体
Alias CLCP1; coagulation factor V/VIII-homology domains protein 1; CUB, LCCL and coagulation factor V/VIII-homology domains protein 1; discoidin CUB and LCCL domain containing 2; Discoidin, CUB and LCCL domain-containing protein 2; endothelial and smooth muscle cell-derived neuropilin-like protein; ESDN; DCBD2_HUMAN.  
Research Area Tumour  Cell biology  immunology  Cell adhesion molecule  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Horse, )
Applications IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 78kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human DCBLD2
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
DCBLD2, otherwise known as ESDN (endothelial and smooth muscle cell-derived neuropilin-like molecule) is a novel type-I transmembrane protein with the longest cleavable secretory signal sequence among eukaryotes. It is expressed in various tissues; particularly highly expressed in cultured vascular smooth muscle cells. DCBLD2 is considered to play a role in regulation of vascular cell growth and may have a wide variety of functions in other tissues including the nervous system, like neuropilins.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Highly expressed in testis, heart, skeletal muscle and also in cultured vascular smooth muscle cells.

Similarity:
Contains 1 CUB domain.
Contains 1 F5/8 type C domain.
Contains 1 LCCL domain.

Database links:

Entrez Gene: 131566 Human

Entrez Gene: 73379 Mouse

Entrez Gene: 155696 Rat

Omim: 608698 Human

SwissProt: Q96PD2 Human

SwissProt: Q91ZV3 Mouse

SwissProt: Q91ZV2 Rat

Unigene: 203691 Human

Unigene: 373589 Mouse

Unigene: 157411 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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