Product Name	Anti-CNGA2/AF594
Chinese Name	AF594标记的环核苷酸阳离子Channel proteinα2抗体
Alias	CNGA2; CNCA; CNCA1; CNG2; FLJ46312; OCNC1; OCNCa;OCNCALPHA; olfactory cyclic nucleotide-gated ion channel alpha subunit; olfactory ion channel protein; Cyclic nucleotide-gated olfactory channel; Cyclic nucleotide-gated cation channel 2; Cyclic nucleotide-gated channel alpha-2; CNG channel alpha-2; CNG-2; Cyclic nucleotide-gated olfactory channel subunit OCNC1; CNGA2_HUMAN.
Research Area	Cardiovascular  Neurobiology  Channel protein
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	73kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human CNGA2 (155-250aa)
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger. CNGA2 belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family and contains one cyclic nucleotide-binding domain. It may be involved in odorant signal transduction. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons. Function: Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons. Subcellular Location: Membrane; Multi-pass membrane protein. Similarity: Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. CNGA2 subfamily. Contains 1 cyclic nucleotide-binding domain. Database links: Entrez Gene: 1260 Human Entrez Gene: 12789 Mouse Entrez Gene: 25411 Rat Omim: 300338 Human SwissProt: Q16280 Human SwissProt: Q62398 Mouse SwissProt: Q00195 Rat Unigene: 447360 Human Unigene: 5097 Mouse Unigene: 10384 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 环核苷酸阳离子Channel proteinα2为阳离子通道结构蛋白。

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