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Product Name Anti-PRCP/AF594 Chinese Name AF594标记的脯氨酰羧肽酶抗体 Alias prolylcarboxypeptidase; Angiotensinase C; HUMPCP; Lysosomal carboxypeptidase C; Lysosomal Pro x carboxypeptidase; PCP; Proline carboxypeptidase. Research Area Kinases and Phosphatases Endocrinopathy Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, Dog, Cow, Horse, ) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 55kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human PRCP Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
PRCP belongs to the peptidase S28 family. It cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH.
Function:
Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH.
Subunit:
Homodimer.
Subcellular Location:
Lysosome.
Tissue Specificity:
Highest levels in placenta, lung and liver. Also present in heart, brain, pancreas and kidney.
Similarity:
Belongs to the peptidase S28 family.
Database links:Entrez Gene: 5547 Human
Omim: 176785 Human
SwissProt: P42785 Human
Unigene: 523936 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PRCP蛋白位于下丘脑,其作用是调节人体内黑素细胞刺激素来遏制人的饥饿感,让人保持精力充沛。 用于从而达到减肥目的。
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