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Rabbit Anti-PRCP/AF594 Conjugated antibody
Rabbit Anti-PRCP/AF594 Conjugated antibody
prolylcarboxypeptidase; Angiotensinase C; HUMPCP; Lysosomal carboxypeptidase C; Lysosomal Pro x carboxypeptidase; PCP; Proline carboxypeptidase.
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  • NO.:SL1873R-AF594
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Mouse,(predicted: Human,Rat,Dog,Cow,Horse,)
    Applications:IF
    concentration:1mg/ml
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Details

Product Name Anti-PRCP/AF594
Chinese Name AF594标记的脯氨酰羧肽酶抗体
Alias prolylcarboxypeptidase; Angiotensinase C; HUMPCP; Lysosomal carboxypeptidase C; Lysosomal Pro x carboxypeptidase; PCP; Proline carboxypeptidase.  
Research Area Kinases and Phosphatases  Endocrinopathy  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Mouse,  (predicted: Human, Rat, Dog, Cow, Horse, )
Applications IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 55kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human PRCP
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
PRCP belongs to the peptidase S28 family. It cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH.

Function:
Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH.

Subunit:
Homodimer.

Subcellular Location:
Lysosome.

Tissue Specificity:
Highest levels in placenta, lung and liver. Also present in heart, brain, pancreas and kidney.

Similarity:
Belongs to the peptidase S28 family.

Database links:

Entrez Gene: 5547 Human

Omim: 176785 Human

SwissProt: P42785 Human

Unigene: 523936 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

PRCP蛋白位于下丘脑,其作用是调节人体内黑素细胞刺激素来遏制人的饥饿感,让人保持精力充沛。 用于从而达到减肥目的。

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