Product Name	Anti-KIR2DS4/CD158i/AF594
Chinese Name	AF594标记的NK细胞抑制性受体2DS4抗体
Alias	Killer cell immunoglobulin-like receptor 2DS4; CD158 antigen like family member I; CD158I; CD158i antigen; CL 17; CL 39; CL17; CL39; Killer cell immunoglobulin like receptor two domains short cytoplasmic tail 4; Killer inhibitory receptor 4 1 2; KIR antigen 2DS4; KIR1D; KIR412; KKA3; MGC120019; MGC125315; MGC125317; MHC class I NK cell receptor; Natural killer associated transcript 8; Natural killer cell inhibitory receptor; NKAT 8; NKAT8; P58 natural killer cell receptor clone CL 39; P58 natural killer cell receptor clone CL39; p58 NK receptor; KI2S4_HUMAN.
Research Area	Cell biology  immunology  Natural killer cells
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,
Applications	IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	31kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human CD158i C-terminus
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: The KIR family consists of transmembrane glycoproteins of the Ig superfamily expressed on human NK cells and a subset of human T cells. They are involved in recognition of either MHC class I molecules or unknown ligand on target cells and inhibit cytotoxic activities. KIR2DS4 is an activating receptor of KIR family. KIR2DS4 is a receptor on natural killer (NK) cells for HLA C alleles. It does not inhibit the activity of NK cells. Function: Receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells. Subcellular Location: Cell membrane; Single-pass type I membrane protein. Similarity: Belongs to the immunoglobulin superfamily. Contains 2 Ig-like C2-type (immunoglobulin-like) domains. Database links: Entrez Gene: 3809 Human Omim: 604955 Human SwissProt: P43632 Human Unigene: 654608 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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