Product Name	Anti-HSD17B2/AF594
Chinese Name	AF594标记的羟类固醇脱氢酶17β2抗体
Alias	11β-HSD2; 17 beta HSD 2; 20 alpha HSD; 20 alpha hydroxysteroid dehydrogenase; E2DH; Microsomal 17 beta hydroxysteroid dehydrogenase; Testosterone 17 beta dehydrogenase; DHB2_HUMAN.
Research Area	Tumour  immunology  Growth factors and hormones  Kinases and Phosphatases
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	43kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human HSD17B2 corresponding to amino acids 187-233.
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: HSD17B2 belongs to the short chain dehydrogenases/reductases (SDR) family. It is capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. It also has 20 alpha HSD activity and uses NADH. Function: Capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. Also has 20-alpha-HSD activity. Uses NADH while EDH17B3 uses NADPH. Subcellular Location: Membrane; Single-pass type II membrane protein. Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. Database links: UniProtKB/Swiss-Prot: P37059.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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