Product Name	Anti-PHYHIP/AF594
Chinese Name	AF594标记的植烷酸氧化酶抗体
Alias	LN1; PAHX; PhyH; PHYH; PHYH1; Phytanic acid oxidase; phytanoyl CoA 2 hydroxylase; Phytanoyl CoA 2 oxoglutarate dioxygenase; Phytanoyl CoA alpha hydroxylase; Phytanoyl CoA dioxygenase; RD antibody; PAHX_HUMAN; Phytanoyl-CoA dioxygenase, peroxisomal; Phytanoyl-CoA alpha-hydroxylase.
Research Area	Tumour  Cell biology  immunology  Neurobiology  transcriptional regulatory factor
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Cow, Rabbit, )
Applications	IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	38kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human PHYH
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: This gene is a member of the PhyH family and encodes a peroxisomal protein that is involved in the alpha-oxidation of 3-methyl branched fatty acids. Specifically, this protein converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA. Mutations in this gene have been associated with Refsum disease (RD) and deficient protein activity has been associated with Zellweger syndrome and rhizomelic chondrodysplasia punctata. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Subunit: Interacts specifically with the immunophilin FKBP52 and PHYHIP. Subcellular Location: Peroxisome. Tissue Specificity: Expressed in liver, kidney, and T-cells, but not in spleen, brain, heart, lung and skeletal muscle. Similarity: Belongs to the PhyH family. Database links: Entrez Gene: 5264 Human Entrez Gene: 16922 Mouse Entrez Gene: 114209 Rat Omim: 602026 Human SwissProt: O14832 Human SwissProt: O35386 Mouse SwissProt: P57093 Rat Unigene: 498732 Human Unigene: 391704 Mouse Unigene: 7279 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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