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Rabbit Anti-Connexin-37/AF594 Conjugated antibody
Rabbit Anti-Connexin-37/AF594 Conjugated antibody
Connexin37; Connexin-37; Connexin 37; CX37; Gap junction alpha 4 protein; gap junction protein, alpha 4 37kDa (connexin 37); gap junction protein, alpha 4, 37kD (connexin 37); GJA4; CXA4_HUMAN; Gap junction alpha-4 protein; OTTHUMP00000004181; OTTHUMP0000
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Product Name Anti-Connexin-37/AF594
Chinese Name AF594标记的间隙连接蛋白37抗体
Alias Connexin37; Connexin-37; Connexin 37; CX37; Gap junction alpha 4 protein; gap junction protein, alpha 4 37kDa (connexin 37); gap junction protein, alpha 4, 37kD (connexin 37); GJA4; CXA4_HUMAN; Gap junction alpha-4 protein; OTTHUMP00000004181; OTTHUMP00000004182.  
Research Area Tumour  immunology  Signal transduction  transcriptional regulatory factor  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human, Mouse,  (predicted: Rat, Pig, Cow, Horse, Rabbit, Guinea Pig, )
Applications IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 37kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human Connexin 37
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
The Connexin 37/GJA4 gene encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction.

Subunit:
A connexon is composed of a hexamer of connexins.

Subcellular Location:
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.

Tissue Specificity:
Expressed in multiple organs and tissues, including heart, uterus, ovary, and blood vessel endothelium.

Database links:

Entrez Gene: 2701 Human

Entrez Gene: 25655 Rat

Omim: 121012 Human

SwissProt: P35212 Human

SwissProt: Q03190 Rat

Unigene: 296310 Human

Unigene: 23406 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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