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Product Name Anti-Connexin-37/AF594 Chinese Name AF594标记的间隙连接蛋白37抗体 Alias Connexin37; Connexin-37; Connexin 37; CX37; Gap junction alpha 4 protein; gap junction protein, alpha 4 37kDa (connexin 37); gap junction protein, alpha 4, 37kD (connexin 37); GJA4; CXA4_HUMAN; Gap junction alpha-4 protein; OTTHUMP00000004181; OTTHUMP00000004182. Research Area Tumour immunology Signal transduction transcriptional regulatory factor Immunogen Species Rabbit Clonality Polyclonal React Species Human, Mouse, (predicted: Rat, Pig, Cow, Horse, Rabbit, Guinea Pig, ) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 37kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Connexin 37 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
The Connexin 37/GJA4 gene encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction.
Subunit:
A connexon is composed of a hexamer of connexins.
Subcellular Location:
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Tissue Specificity:
Expressed in multiple organs and tissues, including heart, uterus, ovary, and blood vessel endothelium.
Database links:Entrez Gene: 2701 Human
Omim: 121012 Human
SwissProt: P35212 Human
Unigene: 296310 Human
Unigene: 23406 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Username | Quantity | bought time |
Ya*** | 2 | 2023-11-25 |
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