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Rabbit Anti-phospho-CTNNBIP1 (Thr43+Ser50)/AF594 Conjugated antibody
Rabbit Anti-phospho-CTNNBIP1 (Thr43+Ser50)/AF594 Conjugated antibody
Beta catenin interacting protein 1; Beta catenin interacting protein ICAT; Catenin beta interacting protein 1; CTNNBIP 1; ICAT; Inhibitor of beta catenin and Tcf 4; MGC15093; CNBP1_HUMAN.
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  • NO.:SL5266R-AF594
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Rat,(predicted: Human,Mouse,Chicken,Cow,Rabbit,)
    Applications:IF
    concentration:1mg/ml
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Product Name Anti-phospho-CTNNBIP1 (Thr43+Ser50)/AF594
Chinese Name AF594标记的磷酸化β链接素相互作用蛋白1抗体
Alias Beta catenin interacting protein 1; Beta catenin interacting protein ICAT; Catenin beta interacting protein 1; CTNNBIP 1; ICAT; Inhibitor of beta catenin and Tcf 4; MGC15093; CNBP1_HUMAN.  
Product Type Phosphorylated anti 
Research Area Cell biology  immunology  Signal transduction  Binding protein  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Rat,  (predicted: Human, Mouse, Chicken, Cow, Rabbit, )
Applications IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 9kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthesised phosphopeptide derived from human CTNNBIP1 around the phosphorylation site of Thr43/Ser50
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
CTNNBIP1 (Catenin, beta interacting protein 1) binds to beta-catenin and prevents the interaction between beta-catenin and TCF transcription factor family members. It is a negative regulator of the Wnt signaling pathway.

Function:
Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt signaling pathway.

Subunit:
Binds CTNNB1.

Subcellular Location:
Cytoplasm (By similarity). Nucleus (By similarity).

Similarity:
Belongs to the CTNNBIP1 family.

Database links:
UniProtKB/Swiss-Prot: Q9NSA3.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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