Product Name	Anti-RASSF4/AF594
Chinese Name	AF594标记的Ras相关区域家族蛋白4抗体
Alias	AD037; Ras association (RalGDS/AF 6) domain family 4; Ras association domain family 4; Ras association (RalGDS/AF 6) domain family member 4; Ras association domain containing protein 4; RASSF 4; Tumor suppressor RASSF4; RASF4_HUMAN.
Research Area	Tumour  Cell biology  immunology  Signal transduction  Cyclin  G protein-coupled receptor
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	37kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human RASSF4
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: The function of RASSF4 has not yet been determined but it may involve a role in tumor suppression. RASSF4 may act as a KRAS effector protein and may promote apoptosis and cell cycle arrest. Alternative splicing of this gene results in several transcript variants; however, most of the variants have not been fully described. Function: Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest. Subunit: Interacts directly with activated KRAS in a GTP-dependent manner. Tissue Specificity: Widely expressed. Frequently down-regulated in tumor cell lines. Similarity: Contains 1 Ras-associating domain. Contains 1 SARAH domain. Database links: Entrez Gene: 83937 Human Entrez Gene: 213391 Mouse Entrez Gene: 362423 Rat Omim: 610559 Human SwissProt: Q9H2L5 Human SwissProt: Q8CB96 Mouse SwissProt: Q566C5 Rat Unigene: 522895 Human Unigene: 257931 Mouse Unigene: 195253 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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