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Rabbit Anti-CIAPIN1/AF594 Conjugated antibody
Rabbit Anti-CIAPIN1/AF594 Conjugated antibody
Anamorsin; CIAPIN 1; Cytokine induced apoptosis inhibitor 1; DRE2; CPIN1_HUMAN.
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Regular members: $476.8
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Details

Product Name Anti-CIAPIN1/AF594
Chinese Name AF594标记的cell factor诱导凋亡抑制因子1
Alias Anamorsin; CIAPIN 1; Cytokine induced apoptosis inhibitor 1; DRE2; CPIN1_HUMAN.  
Research Area Tumour  Cell biology  immunology  Apoptosis  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Pig, Cow, )
Applications IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 34kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human CIAPIN1 (101-200aa)
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
CIAPIN1 (Cytokine induced apoptosis inhibitor 1) expression is dependent on growth factor stimulation. Overexpression confers resistance to apoptosis caused by IL3 deprivation. It may be required during hematopoiesis to mediate antiapoptotic effects of various cytokines. It also confers multidrug resistance in gastric cancer cells by upregulating the expression of MDR1 and MRP1.

Function:
May be required for the maturation of extramitochondrial Fe/S proteins (By similarity). Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells (By similarity).

Subcellular Location:
Cytoplasm. Nucleus.

Tissue Specificity:
Ubiquitously expressed. Highly expressed in heart, liver and pancreas.

Similarity:
Belongs to the anamorsin family.

Database links:

Entrez Gene: 57019 Human

Entrez Gene: 109006 Mouse

Omim: 608943 Human

SwissProt: Q6FI81 Human

SwissProt: Q8WTY4 Mouse

Unigene: 4900 Human

Unigene: 27582 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Partial purchase records(bought amounts latest3)

UsernameQuantitybought time
Ka***22024-08-10
Vi***22024-08-01
Ka***12023-10-05
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