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Rabbit Anti-GLYATL2/AF594 Conjugated antibody
Rabbit Anti-GLYATL2/AF594 Conjugated antibody
Acyl CoA glycine N acyltransferase like protein 2; BXMAS2 10; GATF B; GLYATL2; glycine acyltransferase family B; glycine N acyltransferase like 2; GLYL2_HUMAN.
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  • NO.:SL13449R-AF594
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,)
    Applications:ICC IF
    concentration:1mg/ml
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Product Name Anti-GLYATL2/AF594
Chinese Name AF594标记的甘胺酸-N-酰基转移酶样2抗体
Alias Acyl CoA glycine N acyltransferase like protein 2; BXMAS2 10; GATF B; GLYATL2; glycine acyltransferase family B; glycine N acyltransferase like 2; GLYL2_HUMAN.  
Research Area Tumour  Cell biology  Signal transduction  Stem cells  The new supersedes the old  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, )
Applications ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 34kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human GLYATL2
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
GLYATL2 is a 294 amino acid mitochondrial acyltransferase that transfers the acyl group to the N-terminus of glycine. GLYATL2 can also conjugate a multitude of substrates, including oleoyl-CoA and arachidonoyl-CoA, to form a variety of N-acylglycines. A member of the glycine N-acyltransferase family, GLYATL2 is encoded by a gene that maps to human chromosome 11q12.1. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

Function:
GLYL2 belongs to the glycine N acyltransferase family, and is a mitochondrial acyltransferase which transfers the acyl group to the N terminus of glycine. It can conjugate a multitude of substrates to form a variety of N acylglycines.

Subcellular Location:
Endoplasmic reticulum.

Tissue Specificity:
Expressed at highest levels in salivary gland and trachea. Also detected in thyroid gland, spinal cord, prostate, lung and fetal brain.

Similarity:
Belongs to the glycine N-acyltransferase family.

Database links:
UniProtKB/Swiss-Prot: Q8WU03.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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