TEL: +86 571 56623320 EMAIL: [email protected]
Product Name Anti-GLYATL2/AF594 Chinese Name AF594标记的甘胺酸-N-酰基转移酶样2抗体 Alias Acyl CoA glycine N acyltransferase like protein 2; BXMAS2 10; GATF B; GLYATL2; glycine acyltransferase family B; glycine N acyltransferase like 2; GLYL2_HUMAN. Research Area Tumour Cell biology Signal transduction Stem cells The new supersedes the old Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 34kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human GLYATL2 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
GLYATL2 is a 294 amino acid mitochondrial acyltransferase that transfers the acyl group to the N-terminus of glycine. GLYATL2 can also conjugate a multitude of substrates, including oleoyl-CoA and arachidonoyl-CoA, to form a variety of N-acylglycines. A member of the glycine N-acyltransferase family, GLYATL2 is encoded by a gene that maps to human chromosome 11q12.1. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
Function:
GLYL2 belongs to the glycine N acyltransferase family, and is a mitochondrial acyltransferase which transfers the acyl group to the N terminus of glycine. It can conjugate a multitude of substrates to form a variety of N acylglycines.
Subcellular Location:
Endoplasmic reticulum.
Tissue Specificity:
Expressed at highest levels in salivary gland and trachea. Also detected in thyroid gland, spinal cord, prostate, lung and fetal brain.
Similarity:
Belongs to the glycine N-acyltransferase family.
Database links:
UniProtKB/Swiss-Prot: Q8WU03.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Scan Wechat Qrcode