Product Name	Anti-CST11/AF594
Chinese Name	AF594标记的半胱氨酸蛋白酶抑制剂11抗体
Alias	Cst11; CST11_HUMAN; CST8L; cystatin 11; cystatin related epididymal specific protein; Cystatin-11; dJ322G13.6; SC13; SC13delta.
Research Area	Cell biology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	14kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human CST11
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes an epididymal-specific protein whose specific function has not been determined. Alternative splicing yields two variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] Function: Has antibacterial activity against the Gram-negative bacteria E.coli. May play a role in sperm maturation and fertilization. Subcellular Location: Nucleus. Cytoplasm. Nuclear and cytoplasmic in the epididymis. Localized to the postacrosomal and tail regions of sperm. Probably localized to the outer surface of sperm. Tissue Specificity: Detected in the epithelium and lumen of the epididymis, and in sperm (at protein level). Similarity: Belongs to the cystatin family. Database links: Entrez Gene: 140880 Human Omim: 609731 Human SwissProt: Q9H112 Human Unigene: 128100 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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