Product Name	Anti-HLRC1/AF594
Chinese Name	AF594标记的脱氧双加氧酶抗体
Alias	Deoxyhypusine dioxygenase; Deoxyhypusine hydroxylase; Deoxyhypusine hydroxylase/monooxygenase; Deoxyhypusine monooxygenase; Dohh; DOHH_HUMAN; hDOHH; HEAT like PBS lyase repeat containing; HEAT like repeat containing protein 1; HEAT-like repeat-containing protein 1; MGC4293.
Research Area	Tumour  Cell biology  Signal transduction  The new supersedes the old
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, )
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	33kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human HLRC1
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: This gene encodes a metalloenzyme that catalyzes the last step in the conversion of lysine to the unique amino acid hypusine in eukaryotic initiation factor 5A. The encoded protein hydroxylates deoxyhypusine to form hypusine in the mature eukaryotic initiation factor 5A protein. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Feb 2009] Function: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor. Similarity: Belongs to the deoxyhypusine hydroxylase family. Contains 5 HEAT-like PBS-type repeats. Database links: Entrez Gene: 43740 Fruit fly (Drosophila melanogaster) Entrez Gene: 83475 Human Entrez Gene: 102115 Mouse Entrez Gene: 314644 Rat Entrez Gene: 321732 Zebrafish Omim: 611262 Human SwissProt: Q9V9U4 Fruit fly (Drosophila melanogaster) SwissProt: Q9BU89 Human SwissProt: Q99LN9 Mouse SwissProt: Q5PPJ4 Rat SwissProt: Q7ZUX6 Zebrafish Unigene: 29814 Fruit fly (Drosophila melanogaster) Unigene: 37858 Fruit fly (Drosophila melanogaster) Unigene: 515064 Human Unigene: 609012 Human Unigene: 294975 Mouse Unigene: 38296 Rat Unigene: 2393 Zebrafish Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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